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Description
NTRK1/TrkA Recombinant Rabbit mAb (S-2524-16)Product Specification Host Rabbit Antigen NTRK1 TrkA Synonyms High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1 transforming tyrosine kinase protein; Tropomyosin related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A (Trk A); MTC; TRK; TRKA Immunogen Synthetic Peptide Location Cell membrane Accession P04629 Clone Number S 2524 16 Antibody Type Recombinant mAb Isotype IgG Application WB
Product Specification
| Host | Rabbit |
| Antigen | NTRK1/TrkA |
| Synonyms | High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A (Trk-A); MTC; TRK; TRKA |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P04629 |
| Clone Number | S-2524-16 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Positive Sample | TF-1, K562, SH-SY5Y |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500-1:1000 | Hu |
Background
NTRK1/TrkA, encoded on chromosome 1q23.1, is a 140 kDa high-affinity receptor tyrosine kinase for nerve growth factor (NGF) that, upon ligand-induced dimerization and autophosphorylation at Tyr490, Tyr751 and Tyr785, activates the PI3K/Akt, Ras/MAPK and PLCγ pathways to orchestrate neuronal survival, differentiation, nociception and evasion of apoptosis, while its fusion proteins or mutations can drive oncogenesis and are targeted by TRK inhibitors.
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4.4 ★★★★★
Based on 1575 reviews
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Product Reviews
★★★★★ 5
Mind blowing page turner
Oh my stars!!! 🤯 he falls first and he falls hard, enemies to lovers, fated mates. Every characters are lovable. There's action, magic, one horse 🤭 and a plot twist that keep on twisting. Oh and a bad ass FMC! Loved it!
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Reviewed in the United States on April 23, 2026
★★★★★ 3
Interesting. Confusing ending that's too similar to another book
Ok, I had to process almost a whole 24 hours before I could write this review. And long story short, did I enjoy the book, yes. Does it have a lot of interesting and good parts to it? Also yes. But does it also have some major flaws? Absolutely.
Now I'm not gonna break down every single little thing in this book. But here are the basics of what I liked, and what I didn't like.
The good? I liked the characters. They intrigued me off the bad. The world building is pretty decent. It's a little confusing in the beginning, but information is slowly doled out, and some questions are answered. I found that there was a lot of little twists and turns that kept the story engaging. The magic system is intriguing.
But, there are quite a few things off for me. First off, we have another story that has heavy inspirations from other books. There are a lot of aspects in this story that felt directly pulled from throne of glass. And the big twist at the end? Was almost verbatim the same ending as the book how does it feel. As soon as I read it I was like hold up, I literally just read almost this same thing when I read how does it feel when it released like a year or year and a half ago.
Now I know no concepts are really new anymore, and inspiration comes for everywhere. But I feel like most stories it's like, oh this book has these vibes, or if you liked this book you'd like this one that's similar. But this reminds me of powerless in where there are like exact plots and plot points taken from other things. Now is that a bad thing? Not necessarily. I still enjoyed powerless, and I still enjoyed this story. But it does throw me.
There are also a few red flags that the MMC Acker gave me that were not the good kind of red flags we love. First, when they are riding thru the city and people throw stuff at the FMC and he does nothing? Red flag. When they meet his dad and they demand she vows not only to the king but to the MMC? Red flag. All the secrets he keeps? Red flag. When he SLAPS HER IN THE END? Red flag. I'm not sure how I really feel about him.
In the end. This was still an enjoyable read. I did like it and I am curious about the next book. But I am wary about some of the plot points and the MMC.
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Reviewed in the United States on November 26, 2024
★★★★★ 5
Great book
Format: Kindle
I absolutely feel in love with all 4 characters!!! The bedroom scenes were 🌋🌡🔥🔥🔥. I couldn't put this book down!!! I'm hooked for the whole series Book 2 here I come!!!!! Its a fun easy book and story to read!!
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Reviewed in the United States on October 4, 2024
★★★★★ 4
Fun with a late blooming omega
Format: Kindle
I like this book. The story is fun, cute, and sexy. There's just a little drama, some excellent, steamy scenes, and a fairly good relationship building storyline. I especially like how all the main characters are a bit older than the usual 20 somethings I tend to see in this kind of book.
Having said that, I wish there were more descriptions of the places, as well as the food in the fancy restaurant. I enjoyed the cocktails at the club, so I missed that kind of detail when Gray took Madison on a dinner date. I also wish there had been more interaction between Lucas and Madison, and Lucas and Rian. It felt a bit lopsided, with a focus on Rian, Madison, and Gray.
I wish it had been proofread - there are a lot of typos, but nothing too distracting.
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Reviewed in the United States on September 12, 2022
★★★★★ 3
Madison Deserved Better
Format: Kindle
Madison was a beta...except she wasn't any longer. She was a late presenting Omega. And she was struggling. She was tall and thin, not tiny and curvy. She was opinionated. She was everything an Omega was not. After suffering through her first heat, her friends took her to Ardor, a club where Omegas came to safely find Alphas. She's not expecting much but then she connects with a sexy beta. And when she meets his Alphas, they set her body on fire. Maybe, she's found her no-strings-attached heat pack. Maybe, she's found something more.
I could not connect with the characters in this book, so their story never resonated with me. And there was no love story; there was sex. Grey made it clear from the beginning that he had a true love and it was his beta boy, Rian. He went so far as to reassure Rian “Say the word, I’ll never touch her again. Lucas can put the babies in her. I only need you, beta boy”. So, Madison was there for babies, no emotions needed. Nice. No, thank you. I want the Omega to be the center of their world, not an incubator. Lucas and Rian weren't any better. After her heat, they let her leave. Not one of them made her feel valued. No one gave her a reason to stay or even offered a cuddle. And the sex didn't even come across as mind-blowing. Madison deserved better.
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Reviewed in the United States on March 11, 2025