Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 6 - Jul 11
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 647 Mouse Anti-Human CD24 Antibody (S-R576)Product Specification Host Mouse Antigen CD24 Synonyms Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24A Location Cell membrane Accession P25063 Clone Number S R576 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Mouse |
| Antigen | CD24 |
| Synonyms | Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24A |
| Location | Cell membrane |
| Accession | P25063 |
| Clone Number | S-R576 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Hu |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Hu |
Background
CD24 is a highly glycosylated cell surface protein that is anchored to the cell membrane via a glycosyl-phosphatidylinositol (GPI) anchor. It is widely expressed in various cell types, including hematopoietic cells such as B cells, T cells, granulocytes, dendritic cells, and macrophages, as well as non-hematopoietic cells like keratinocytes and neurons. CD24 plays a crucial role in immune cell maturation and regulation of immune responses. In cancer, CD24 is overexpressed on tumor cells and interacts with the inhibitory receptor Siglec-10 on immune cells, helping tumor cells evade immune detection and attack. This interaction has led to its exploration as a potential target for cancer immunotherapy, with promising results from clinical trials of monoclonal antibodies and other targeted therapies.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy