Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 7 - Jul 12
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Mouse Anti-Human CD148 Antibody (S-3121)Product Specification Host Mouse Antigen CD148 Synonyms Receptor type tyrosine protein phosphatase eta; Protein tyrosine phosphatase eta; R PTP eta; Density enhanced phosphatase 1 (DEP 1); HPTP eta; Protein tyrosine phosphatase receptor type J (R PTP J); DEP1; PTPRJ Location Cell membrane Accession Q12913 Clone Number S 3121 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human peripheral blood Leukocyte
Product Specification
| Host | Mouse |
| Antigen | CD148 |
| Synonyms | Receptor-type tyrosine-protein phosphatase eta; Protein-tyrosine phosphatase eta; R-PTP-eta; Density-enhanced phosphatase 1 (DEP-1); HPTP eta; Protein-tyrosine phosphatase receptor type J (R-PTP-J); DEP1; PTPRJ |
| Location | Cell membrane |
| Accession | Q12913 |
| Clone Number | S-3121 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human peripheral blood Leukocyte |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
CD148 (also called PTPRJ or DEP-1) is a ~220 kDa receptor-type protein tyrosine phosphatase of the R3 subfamily that contains an extracellular region with eight fibronectin III-like repeats, a single transmembrane segment, and an intracellular catalytic domain; it is broadly expressed in hematopoietic and non-hematopoietic cells where it functions as a key negative regulator of growth-factor and adhesion signaling by dephosphorylating receptor tyrosine kinases such as PDGFR, VEGFR, EGFR, and Eph receptors, thereby inhibiting downstream PI3K/AKT, MAPK, and Src-family kinase pathways, promoting contact-inhibited growth, stabilizing cadherin-mediated cell–cell junctions, and acting as a tumor suppressor whose loss or down-regulation is associated with enhanced proliferation, migration, and metastasis in cancers of the stomach, colon, lung, thyroid, and breast.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.5 ★★★★★
Based on 2354 reviews
Sort
Product Reviews
★★★★★ 5
Wow, a great surprise dark comedy from the 1970s!
A real treat from Michael Ritchie (The Golden Child) with an excellent script, an A+ cast and plenty of action, despite the fact that it's really a very dark – almost surreal – comedy/satire about the meat industry in the 'American Heartland.'
As usual, Lee Marvin, Gene Hackman and Sissy Spacek bring their best work. very graphic cinematography, real physical special effects (no CGI) and good plot twists make it a riveting experience.
Highly recommended for those who like their dark satires well-done!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 15, 2024
★★★★★ 5
Lots of Action in this 70s Movie
I bought this movie for my husband and he really liked this 70s movie.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 4, 2026
★★★★★ 5
Not well known, but should be!
Two of my favorite male actors of all time creating an interesting movie, this one has it all!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 20, 2026
★★★★★ 4
Minor classic that pits Lee Marvin and Gene Hackman in thriller.
A terrific neo noir with touches of Hitchcock, “Prime Cut” revels in the cliches of many of the genres- the criminal with the heart of gold and the sleazy underworld of the bad guys.
Spoilers:
Set in the Heartland, the film. Follows Nick (Lee Marvin) an enforcer hired by the Irish Mob who is send to collect from Mary Ann (Gene Hackman-really!) the owner of a meat packing planet who has a prostitution racket on the side for young and underage girls. Mary Ann had been stiffing the Mob on a debt and each enforcer has been killed and sent back in an interesting way. Nick is horrified at the prostitution ring that Mary Ann runs; they have history as well and that history plays into the animosity of both men as they fight it out Ina thrilling conclusion. Towards the end of his career as an enforcer, Nick disliked the way his world has turned out.
Michael Richtie was at the beginning of his career as a director but was clearly in control as a director staging some thrilling scenes with echoes of Hitchcock’s classics “North by Northwest” and other classics. Richtie doesn’t ape Hitch so much as may the sequences work in the context of his film.
The 4 K and Blu-ray look terrific from a fresh transfer of the original camera negative. There’s virtually no issues with the films. Colors are strong, detail excellent and it looks of its time without any messing about with the image.
The mono audio pushes dialogue up front but there is a nice, robust feel to the rest of the mono soundtrack.
The film has two commentary tracks both very good (one has to use the audio selection to hear them as I didn’t see it in the main menu for the 4K). We find out, for example, that Hackman took his second billed role because he had just finished “The French Connection” and hadn’t worked for six months. Richtie and Marvin butted heads because Richtie wanted Marvin to do a love scene with the much younger Sissy Spacek in her debut. Marvin felt uncomfortable with that because of their age difference (she was 23 and Marvin was 49).
A Blu-ray (that was previously released a couple of years back) is also included. Kino has done a fine job of brining this minor classic to 4K and Blu-ray. One may feel like they need to take a shower after watching the film because of how sleazy Hackman plays an already nasty character like Mary Ann. Putting this in the heartland with all the corruption of the big city adds an element that is missing from many films like this. The corruption at heart of Mary Ann and the community he has tainted by his presence points to the rot that was growing in America at the time.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 21, 2024
★★★★★ 5
RIP Gene Hackman…Holy $?#! This movie!
Prime Cut is honestly more a 3 1/2 star movie however KINO gets 5 stars for releasing a beautiful transfer of this mean & nasty 70s crime drama that’s as violent as it is weird. Hackman as the Kansas City Gangster who makes enemies into hotdogs before sending them back, draws the ire of Chicago enforcer Marvin to collect a large sum of money from Mary Ann - Hackman’s name by the way. The Blu Ray doesn’t have much but if you like sleazy, mean, & odd 70s crime thrillers, take a hefty bite of this PRIME CUT.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 6, 2025
recommand products
14k Yellow Gold Polished Classic 21.6mm Coin Bezel Cuff Links - Fits US $5 Bald Eagle, US $5 Congressional, US $5 Liberty, and Other Coins
907.00
AutoMeter Battery Tester (SB-3)
327.64
AutoMeter Tachometer Gauge (200752-35)
109.65
AutoMeter Pro-Cycle Gauge Tach/Speedo 4 1/2in 8K Rpm/120 Mph Black (19466)
197.41
AutoMeter Intelli-Check II Heavy Duty Truck Electrical System Analyzer (BCT-200J)
785.99